N-Oleoylphenylalanine | Endogenous Uncoupler of Mitochondrial Respiration
NMR (Conforms)
Blue Ice
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $50.00 | ||
| 25 mg | $200.00 |
N-Oleoylphenylalanine (136560-78-6) is an endogenous lipoamino acid produced via the action of a secreted enzyme PM20D1 produced by adipocytes. N-Oleoylphenylalanine binds directly to mitochondria and functions as an endogenous uncoupler of UCP1-independent respiration and is the most potent in the group of structurally different lipoamino acids evaluated. Mice treated with an analog, C18-1-Leu, were found to have improved glucose homeostasis and increased energy expenditure.1
References/Citations:
1) Long et al. (2016), The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria; Cell, 166 424
NMR (Conforms)
Blue Ice
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
N-Oleoylphenylalanine (136560-78-6) is an endogenous lipoamino acid produced via the action of a secreted enzyme PM20D1 produced by adipocytes. N-Oleoylphenylalanine binds directly to mitochondria and functions as an endogenous uncoupler of UCP1-independent respiration and is the most potent in the group of structurally different lipoamino acids evaluated. Mice treated with an analog, C18-1-Leu, were found to have improved glucose homeostasis and increased energy expenditure.1
References/Citations:
1) Long et al. (2016), The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria; Cell, 166 424
Related products
-
RHC-80267 | DAG Lipase inhibitor
From $55.00CAS:83654-05-1Catalog Number:10-1051Activity:DAG Lipase inhibitorAlternate Names:U-57908Chemical Name:1,6-bis(Cyclohexyloximinocarbonyl-amino)hexaneMolecular Weight:394.53Molecular Formula:C20H34N4O4Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:Off-white solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 monthsShipping Code:RT -
MK-886 | FLAP inhibitor
From $70.00CAS:118414-82-7Catalog Number:10-1040Activity:FLAP inhibitorAlternate Names:L-663,536Chemical Name:3-[1-(4-Chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acidMolecular Weight:472.08Molecular Formula:C27H34ClNO2SSolubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
NA-Gly | GPR18 agonist
From $60.00CAS:179113-91-8Catalog Number:10-1200Activity:GPR18 agonistAlternate Names:N-ArachidonylglycineChemical Name:N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)glycineMolecular Weight:361.53Molecular Formula:C22H35NO3Solubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:Beige waxy solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Product is subject to oxidation. Solutions in degassed DMSO may be stored at -20°C for up to 1 month.Shipping Code:Blue Ice
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
