Nafamostat Mesylate | Serine protease inhibitor

CAS:
82956-11-4
Catalog Number:
10-1089
Activity:
Serine protease inhibitor
Alternate Names:
Futhan; FUT-175
Chemical Name:
6-Amidino-2-naphthyl-4-guanidinobenzoate dimesylate
Molecular Weight:
539.59
Molecular Formula:
C19H17N5O2·2CH4O3S
Solubility:
Soluble in Water (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at 4°C for up to 1 month, or at -80°C for up to 6 months.
Shipping Code:
RT

Available Options

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10 mg$50.00
50 mg$200.00
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Nafamostat mesylate (82956-11-4) is a potent and reversible serine protease inhibitor (IC50‘s range from 0.3 – 54.0 μM). Inhibits the demethylase activity of the fat mass and obesity-associated protein (FTO).1 Cell permeable. Intended for cell culture or in vivo laboratory experimentation. This product is not approved for human therapeutic use.

References/Citations:

1) Han et al. (2019) Identification of nafamostat mesilate as an inhibitor of the fat mass and obesity-associated protein (FTO) demethylase; Chem. Biol. Interact., 297 80

CAS:
82956-11-4
Catalog Number:
10-1089
Activity:
Serine protease inhibitor
Alternate Names:
Futhan; FUT-175
Chemical Name:
6-Amidino-2-naphthyl-4-guanidinobenzoate dimesylate
Molecular Weight:
539.59
Molecular Formula:
C19H17N5O2·2CH4O3S
Solubility:
Soluble in Water (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at 4°C for up to 1 month, or at -80°C for up to 6 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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