Naloxone HCl | Opioid receptor antagonist
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 100 mg | $95.00 | ||
| 500 mg | $280.00 |
Naloxone (357-08-4) is a pan-opioid receptor antagonist, Ki=3.7, 9.2 and 33 nM for m, k and d opioid receptors respectively.1 In clinical use in opiate abuse and overdose rescue.2 Blocks opiate- promoted wound healing.3 Attenuates the pruritic response to rimonabant in a rat model.4
References/Citations
1) Le Bourdonnec et al., (2008), Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles: Bioorg. Med. Chem. Lett.. 18 2006
2) Boyer et al. (2012), Management of opioid analgesic overdose; New Engl. J. Med. 367 146
3) Wang et al. (2017), Opioids and opioid receptors orchestrate wound repair; Transl. Res. 185 13
4) Wright and Rodgers (2013), Low dose naloxone attenuates the pruritic but not anorectic response to rimonabant in male rats; Psychopharmacology (Berl.) 226 415
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Naloxone (357-08-4) is a pan-opioid receptor antagonist, Ki=3.7, 9.2 and 33 nM for m, k and d opioid receptors respectively.1 In clinical use in opiate abuse and overdose rescue.2 Blocks opiate- promoted wound healing.3 Attenuates the pruritic response to rimonabant in a rat model.4
References/Citations
1) Le Bourdonnec et al., (2008), Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles: Bioorg. Med. Chem. Lett.. 18 2006
2) Boyer et al. (2012), Management of opioid analgesic overdose; New Engl. J. Med. 367 146
3) Wang et al. (2017), Opioids and opioid receptors orchestrate wound repair; Transl. Res. 185 13
4) Wright and Rodgers (2013), Low dose naloxone attenuates the pruritic but not anorectic response to rimonabant in male rats; Psychopharmacology (Berl.) 226 415
Related products
-
SAHA | HDAC inhibitor
From $35.00CAS:149647-78-9Catalog Number:10-1067Activity:HDAC inhibitorAlternate Names:VorinostatChemical Name:Suberoylanilide-hydroxamic acidMolecular Weight:264.33Molecular Formula:C14H20N2O3Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.Shipping Code:RT -
Phenylbutyrate Na | HDAC inhibitor
From $35.00CAS:1716-12-7Catalog Number:10-1118Activity:HDAC inhibitorAlternate Names:4-PB, PBNaChemical Name:4-Phenylbutyric acid sodium saltMolecular Weight:186.18Molecular Formula:C10H11NaO2Solubility:Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Mupirocin | Antibiotic
From $80.00CAS:12650-69-0Catalog Number:10-1101Activity:AntibioticAlternate Names:Pseudomonic acid AMolecular Weight:500.63Molecular Formula:C26H44O9Solubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:Hygroscopic colorless wax/amorphous solidPurity:>98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
