Nilotinib | BCR-ABL inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $30.00 | ||
| 25 mg | $90.00 |
Nilotinib (CAS 641571-10-0) is a novel, selective BCR-ABL inhibitor. More potent than imatinib against wild-type BCR-ABL (IC50 < 30 nM).1 Induces apoptosis.2
References/Citations:
1) Weisberg et al. (2006), AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL; Br J. Cancer, 94 1765
2) Verstovsek et al. (2006), Activity of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, against human FIP1L1-PDGFR-alpha-expressing cells; Ann. Neurol., 75 209
NMR (Conforms)
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Product Data Sheet:
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Nilotinib (CAS 641571-10-0) is a novel, selective BCR-ABL inhibitor. More potent than imatinib against wild-type BCR-ABL (IC50 < 30 nM).1 Induces apoptosis.2
References/Citations:
1) Weisberg et al. (2006), AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL; Br J. Cancer, 94 1765
2) Verstovsek et al. (2006), Activity of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, against human FIP1L1-PDGFR-alpha-expressing cells; Ann. Neurol., 75 209
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