Noopept | Nootropic and neuroprotective agent

CAS:
157115-85-0
Catalog Number:
10-2682
Short Description:
Nootropic and neuroprotective agent
Chemical Name:
1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester
Alternate Names:
SGS-111; GVS 111
Molecular Weight:
318.37
Molecular Formula:
C17H22N2O4
Solubility:
Soluble in DMSO (up to 25 mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
10 mg$50.00
50 mg$175.00

Noopept (157115-85-0) is a novel proline-containing dipeptide with nootropic and cognition-enhancing activity.1 Rescues α-synuclein amyloid toxicity in cellular models.2 Stimulates the expression of NGF and BDNF in rat hippocampus.3 Improves viability of hippocampal HT-22 neurons in a glutamate toxicity model.4 Normalizes blood glucose level and tolerance to glucose load in a streptozotocin diabetic rat model of developing diabetes.5

References/Citations:

1) Ostrovskaya et al. (2007), The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer’s disease model; J. Psychopharmacol., 21 611
2) Jia et al. (2011), Neuroprotective and nootropic drug noopept rescues α-synuclein amyloid cytotoxicity; J. Mol. Biol., 414 699
3) Ostrovskaya et al. (2008), Noopept stimulates the expression of NGF and BDNF in rat hippocampus; Bull. Exp. Biol. Med., 146 334
4) Antipova et al. (2016), Dipeptide Piracetam Analogue Noopept Improves Viability of Hippocampal HT-22 Neurons in the Glutamate Toxicity Model; Bull. Exp. Biol. Med., 161 58
5) Ostrovskaya et al. (2014), Comparative activity of proline-containing dipeptide noopept and inhibitor of dipeptidyl peptidase-4 sitagliptin in a rat model of developing diabetes; Bull. Exp. Biol. Med., 156 342

CAS:
157115-85-0
Catalog Number:
10-2682
Short Description:
Nootropic and neuroprotective agent
Chemical Name:
1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester
Alternate Names:
SGS-111; GVS 111
Molecular Weight:
318.37
Molecular Formula:
C17H22N2O4
Solubility:
Soluble in DMSO (up to 25 mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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