NSC66811 | p53/mdm2 inhibitor
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $100.00 | ||
| 50 mg | $400.00 |
NSC66811 (6964-62-1) is a novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. NSC-66811 binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.
References/Citations:
1) Lu et al. (2006), Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy; J. Med. Chem., 49 3759
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
NSC66811 (6964-62-1) is a novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. NSC-66811 binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.
References/Citations:
1) Lu et al. (2006), Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy; J. Med. Chem., 49 3759
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