NVS-STG2 | Molecular glue STING agonist
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $75.00 | ||
| 25 mg | $265.00 |
NVS-STG2 (3030588-01-0) is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 µM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.
References/Citations:
- Li et al. (2024), Activation of human STING by a molecular glue-like compound; Nat.Chem. Biol. 20 365
C25H33NO5
>98% HPLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
NVS-STG2 (3030588-01-0) is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 µM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.
References/Citations:
- Li et al. (2024), Activation of human STING by a molecular glue-like compound; Nat.Chem. Biol. 20 365
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