Optovin | TRPA1 channel activator
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $70.00 | ||
| 25 mg | $280.00 |
Optovin (348575-88-2) is a reversible photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM) and mice, in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1
References/Citations:
1) Kokel et al. (2013), Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol., 9 257
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
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Optovin (348575-88-2) is a reversible photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM) and mice, in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1
References/Citations:
1) Kokel et al. (2013), Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol., 9 257
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