Oseltamivir Phosphate | Neuraminidase inhibitor / Antiviral

CAS:
204255-11-9
Catalog Number:
10-4483
Activity:
Neuraminidase inhibitor / Antiviral
Chemical Name:
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate phosphoric acid salt
Alternate Name:
GS4104; Tamiflu
Molecular Weight:
410.40
Molecular Formula:
C16H28N2O4•H3PO4
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Water (up to at least 40 mg/ml).
Physical Properties:
White solid
Purity:
99% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
50 mg$30.00
250 mg$110.00

Oseltamivir phosphate (204255-11-9) is a potent viral neuraminidase inhibitor and a clinically useful treatment for influenzas A and B.1,2 Oseltamivir is a prodrug that is converted to the active acid in vivo – IC50 for active acid in vitro = 2 nM.3

References/Citations:

1) Sidwell et al. (1998), Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor; Antiviral Res., 37 107
2) McClellan and Perry (2001), Oseltamivir: A Review of Its Use in Influenza; Drugs, 61 263
3) Li et al. (1998), Identification of GS4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS4071; Antimicrob. Agents Chemother., 42 647

CAS:
204255-11-9
Catalog Number:
10-4483
Activity:
Neuraminidase inhibitor / Antiviral
Chemical Name:
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate phosphoric acid salt
Alternate Name:
GS4104; Tamiflu
Molecular Weight:
410.40
Molecular Formula:
C16H28N2O4•H3PO4
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Water (up to at least 40 mg/ml).
Physical Properties:
White solid
Purity:
99% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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