OTUDin3 | OTUD3 inhibitor
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $70.00 | ||
| 25 mg | $250.00 |
OTUDin3 (441290-65-9) is a potent inhibitor of the deubiquitinase OTUD3, a member of the ovarian tumor proteases which plays a key role in tumorigenesis, neurodegeneration, metabolism, and immunity. It inhibited non-small cell lung cancer growth, migration, and invasion via enhancing the ubiquitination and degradation of the anti-apoptotic protein GRP78. OTUDin3 inhibited lung cancer growth in an H1299 mouse xenograft model.
References/Citations:
- Zhang, et al. (2023), Discovery of an OTUD3 inhibitor for the treatment of non-small cell lung cancer; Cell Death Dis., 14 378
C29H24N4O3S
>98% by HPLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
OTUDin3 (441290-65-9) is a potent inhibitor of the deubiquitinase OTUD3, a member of the ovarian tumor proteases which plays a key role in tumorigenesis, neurodegeneration, metabolism, and immunity. It inhibited non-small cell lung cancer growth, migration, and invasion via enhancing the ubiquitination and degradation of the anti-apoptotic protein GRP78. OTUDin3 inhibited lung cancer growth in an H1299 mouse xenograft model.
References/Citations:
- Zhang, et al. (2023), Discovery of an OTUD3 inhibitor for the treatment of non-small cell lung cancer; Cell Death Dis., 14 378
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