OX04528 | GPR84 agonist

CAS:
3028055-45-7
Catalog Number:
10-4285
Activity:
GPR84 agonist
Chemical Names:
3-(3-(3,5-Bis(trifluoromethyl)phenyl)propyl)-5-hydroxypyridine-1-oxide
Molecular Weight:
365.28
Molecular Formula:
C16H13F6NO2
Solubility:
Soluble in DMSO (50 mg/ml)
Physical Properties:
White solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$80.00
25 mg$295.00

OX04528 (3028055-45-7) is a very potent (cAMP EC50 = 5.98 pM), selective (inactive at GPR40, GPR120, and CB2), and orally bioavailable GPR84 agonist with no detectable effects on ß-arrestin recruitment.  A potent new chemical tool to probe the role of GPR84 in cancer, inflammatory, and fibrotic diseases.

References/Citations:

  1. Wang et al. (2024), Development of Highly Potent, G-Protein Biased, Selective, and Orally Bioavailable GPR84 Agonists; J. Med. Chem. 67 110
CAS:
3028055-45-7
Catalog Number:
10-4285
Activity:
GPR84 agonist
Chemical Names:
3-(3-(3,5-Bis(trifluoromethyl)phenyl)propyl)-5-hydroxypyridine-1-oxide
Molecular Weight:
365.28
Molecular Formula:
C16H13F6NO2
Solubility:
Soluble in DMSO (50 mg/ml)
Physical Properties:
White solid
Purity:
>98% HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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