Size: | Price | Quantity | |
---|---|---|---|
5 mg | $60.00 | ||
25 mg | $210.00 |
P053 (1022417-69-1) is a selective inhibitor of protein phosphatase 5 (PP5) – IC50 = 706 nM.1 PP5 regulates signaling cascades that are responsible for tumor initiation, progression, and metastasis and is thus an interesting anticancer target. P053 induced apoptosis in 786-O renal carcinoma cells. Inhibition of PP5 by P053 prevents deactivation of the death effector protein FADD and activates the extrinsic apoptosis pathway complex II.
References/Citations:
C18H18N2O3S
>98% by HPLC
NMR: (Conforms)
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
P053 (1022417-69-1) is a selective inhibitor of protein phosphatase 5 (PP5) – IC50 = 706 nM.1 PP5 regulates signaling cascades that are responsible for tumor initiation, progression, and metastasis and is thus an interesting anticancer target. P053 induced apoptosis in 786-O renal carcinoma cells. Inhibition of PP5 by P053 prevents deactivation of the death effector protein FADD and activates the extrinsic apoptosis pathway complex II.
References/Citations:
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
For Postdoc
Customers!
Website Created by Advanta Advertising LLC.