PD-1/PD-L1 Inhibitor 1

CAS:
1675201-83-8
Catalog Number:
10-4901
Activity:
PD-1/PD-L1 inhibitor
Chemical Name:
(2S)-1-[[2,6-Dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]pipieridine-2-carboxylic acid
Alternate Name:
BMS-3
Molecular Weight:
475.59
Molecular Formula:
C29H33N2O5
Solubility:
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 20 mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$95.00
25 mg$335.00

PD-1/PD-L1 Inhibitor 1 (1675201-83-8) inhibits (IC50 = <100nM) the formation of the PD-1/PD-L1 complex via binding to PD-L1 and inducing dimerization.1

References/Citations:

1) Chupak et al. (2015), Compounds Useful as Immunomodulators; WO2015/034820

CAS:
1675201-83-8
Catalog Number:
10-4901
Activity:
PD-1/PD-L1 inhibitor
Chemical Name:
(2S)-1-[[2,6-Dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]pipieridine-2-carboxylic acid
Alternate Name:
BMS-3
Molecular Weight:
475.59
Molecular Formula:
C29H33N2O5
Solubility:
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 20 mg/ml)
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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