Phenylbutyrate Na | HDAC inhibitor

CAS:
1716-12-7
Catalog Number:
10-1118
Activity:
HDAC inhibitor
Alternate Names:
4-PB, PBNa
Chemical Name:
4-Phenylbutyric acid sodium salt
Molecular Weight:
186.18
Molecular Formula:
C10H11NaO2
Solubility:
Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
1 gram$35.00
5 gram$95.00

Phenylbutyrate Na (1716-12-7) is a histone deacetylase (HDAC) inhibitor. Inhibits proliferation, migration and invasion of a number of cancer cell lines. Phenylbutyrate Na induces differentiation, and apoptosis. Active in vivo.

References/Citations:

1) Engelhard et al. (1998), Inhibitory effects of phenylbutyrate on the proliferation, morphology, migration and invasiveness of malignant glioma cells; J. Neuro-Oncol., 37 97
2) Appelskog et al. (2004), Histone deacetylase inhibitor 4-phenylbutyrate suppresses GAPDH mRNA expression in glioma cells; Int. J. Oncol., 24 1419

CAS:
1716-12-7
Catalog Number:
10-1118
Activity:
HDAC inhibitor
Alternate Names:
4-PB, PBNa
Chemical Name:
4-Phenylbutyric acid sodium salt
Molecular Weight:
186.18
Molecular Formula:
C10H11NaO2
Solubility:
Soluble in DMSO (up to 4 mg/ml) or in Water (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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