PNU 74654 | Wnt pathway blocker
NMR (conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $55.00 | ||
| 25 mg | $185.00 |
PNU 75654 (113906-27-7) disrupts the Wnt signaling pathway via inhibition of the interaction (KD50 = 450 nM) between β-catenin and T cell factor 4 (Tcf4).
References/Citations:
1) Trosset et al. (2006) Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening; Proteins, 64 60
NMR (conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
PNU 75654 (113906-27-7) disrupts the Wnt signaling pathway via inhibition of the interaction (KD50 = 450 nM) between β-catenin and T cell factor 4 (Tcf4).
References/Citations:
1) Trosset et al. (2006) Inhibition of protein-protein interactions: the discovery of druglike beta-catenin inhibitors by combining virtual and biophysical screening; Proteins, 64 60
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