N-Acetyl-L-cysteine | Antioxidant

CAS:
616-91-1
Catalog Number:
10-2321
Activity:
Antioxidant
Chemical Names:
(R)-2-Acetamido-3-mercaptopropanoic acid
Alternate Name:
N-Acetylcysteine; NAC; NSC-111180
Molecular Weight:
163.19
Molecular Formula:
C5H9NO3S
Solubility:
Soluble in DMSO (50 mg/ml); water (30 mg/ml)
Physical Properties:
White solid
Purity:
>98% TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Make solutions fresh daily – do not store in solution.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 g$25.00
25 g$58.00

N-Acetyl-L-cysteine (616-91-1) is a thiol-containing antioxidant.1 N-Acetyl-L-cysteine acts as a scavenger of reactive oxygen species (ROS) and is commonly used to decrease oxidative stress in various models.2 Inhibits ROS-dependent apoptosis.3 Displays protective effects in various disease models including renal ischemia/reperfusion injury4, hepatic failure5 and others. Has been shown to interfere with and antagonize the activity of proteasome inhibitors.6

References/Citations:

  1. Merck Index 14 88
  2. Mlejnek et al. (2022), Direct Interaction between N-Acetylcysteine and Cytotoxic Electrophile – An Overlooked In Vitro Mechanism of Protection; Antioxidants (Basel), 11 1485
  3. Curtin et al. (2002), Regulation and measurement of oxidative stress in apoptosis; J. Immunol. Methods, 265 49
  4. Sehirli et al. (2003), Protective effect of N-acetylcysteine on renal ischemia/reperfusion injury in the rat; J. Nephrol. 16 75
  5. Ritter et al. (2004), Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced hepatic failure in rats; Crit. Care Med. 32 2079
  6. Halasi et al. (2033), ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors; Biochem. J. 454 201
CAS:
616-91-1
Catalog Number:
10-2321
Activity:
Antioxidant
Chemical Names:
(R)-2-Acetamido-3-mercaptopropanoic acid
Alternate Name:
N-Acetylcysteine; NAC; NSC-111180
Molecular Weight:
163.19
Molecular Formula:
C5H9NO3S
Solubility:
Soluble in DMSO (50 mg/ml); water (30 mg/ml)
Physical Properties:
White solid
Purity:
>98% TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Make solutions fresh daily – do not store in solution.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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