Punicalagin | Anti-inflammatory
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $25.00 | ||
| 5 mg | $95.00 |
Punicalagin (65995-63-3) is a polyphenolic compound isolated from pomegranates possessing antioxidant, anti-inflammatory, and antitumorigenic properties.1,2 It has been shown to reduce high glucose-induced neural tube defects by blocking cellular stress and caspase activation.3 Punicalagin prevented high-fat diet induced obesity associated accumulation of cardiac triglyceride and cholesterol as well as myocardial damage via AMPK mediated modulation of mitochondria and phase II enzymes.4
References/Citations:
1) Seeram et al. (2005), In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice; J. Nutr. Biochem., 16 360
2) Adams et al. (2006), Pomegranate Juice, Total Pomegranate Ellagitannins, and Punicalagin Suppress Inflammatory Cell Signaling in Colon Cancer Cells; J. Agric. Food Chem., 54 980
3) Zhong et al. (2015), Punicalagin exerts protective effect against high glucose-induced cellular stress and neural tube defects; Biochem. Biophys. Res. Commun., 467 179
4) Cao et al. (2015), Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activation; Sci. Rep., 5 14014
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Punicalagin (65995-63-3) is a polyphenolic compound isolated from pomegranates possessing antioxidant, anti-inflammatory, and antitumorigenic properties.1,2 It has been shown to reduce high glucose-induced neural tube defects by blocking cellular stress and caspase activation.3 Punicalagin prevented high-fat diet induced obesity associated accumulation of cardiac triglyceride and cholesterol as well as myocardial damage via AMPK mediated modulation of mitochondria and phase II enzymes.4
References/Citations:
1) Seeram et al. (2005), In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice; J. Nutr. Biochem., 16 360
2) Adams et al. (2006), Pomegranate Juice, Total Pomegranate Ellagitannins, and Punicalagin Suppress Inflammatory Cell Signaling in Colon Cancer Cells; J. Agric. Food Chem., 54 980
3) Zhong et al. (2015), Punicalagin exerts protective effect against high glucose-induced cellular stress and neural tube defects; Biochem. Biophys. Res. Commun., 467 179
4) Cao et al. (2015), Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activation; Sci. Rep., 5 14014
Related products
-
Fatostatin | SREBP activation inhibitor
From $50.00CAS:125256-00-0Catalog Number:10-1355Activity:SREBP activation inhibitorChemical Name:2-(2-Propylpyridin-4-yl)-4-(p-tolyl)thiazoleMolecular Weight:294.42Molecular Formula:C18H18N2SSolubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
SR1001 | RORα gamma inverse agonist
From $80.00CAS:1335106-03-0Catalog Number:10-1290Activity:RORα inverse agonistChemical Name:N-(5-(N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)sulphamoyl)-4-methylthiazol-2-yl)acetamideMolecular Weight:477.39Molecular Formula:C15H13F6N6O4S2Solubility:Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 40 mg/ml).Physical Properties:Pale beige solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Amlexanox | TBK1 inhibitor / Antidiabetic
From $40.00CAS:68302-57-8Catalog Number:10-1435Activity:TBK1 inhibitor / AntidiabeticChemical Name:2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acidMolecular Weight:298.29Molecular Formula:C16H14N2O4Solubility:Soluble in DMSO (up to 60 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
