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Raf kinase drug successRaf kinase drug successRaf kinase drug successRaf kinase drug success
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    • Biochemical Targets
      • Autophagy
      • Bioactive Lipids
      • Cellular Metabolism
      • Cellular trafficking
      • Cytoskeleton
      • DNA Damage/Repair
      • Epigenetics
      • Gene regulation
      • GPCRs
      • Ions and other channels
      • Kinases
      • Mitochondria
      • Nuclear receptors
      • Transcription factors
      • Ubiquitin/Proteasome
      • View All
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      • Bioprocessing
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      • Cardiovascular
      • Cell Cycle
      • Cellular Senescence
      • Cellular Stress
      • Circadian clock
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Visit Focus Biomolecules at ASBMB
March 4, 2026
Visit Focus Biomolecules at AACR
April 14, 2026

Raf kinase drug success

Published by Focus Biomolecules on March 12, 2026

FOCUS on a New Pharma Success Story. Day One Biopharmaceuticals is only 8 years old, yet in that short period of time it bought the rights to MLN2480 (TAK580; a Raf kinase inhibitor originally developed in a collaboration between Sunesis and Biogen) and successfully pushed it forward to FDA approval in April of 2024, for patients with relapsed or refractory pediatric low-grade glioma harboring a BRAF fusion or rearrangement, or BRAF V600 mutation. This month, Day One announced its acquisition by Servier Pharmaceuticals for $2.5 billion!

Focus Biomolecules can supply Tovorafenib (MLN2480) for research applications. For more information contact us.

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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