Immunoregulatory Kinases
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Acalabrutinib | Highly selective BTK inhibitor
From $45.00CAS:1420477-60-6Catalog Number:10-4806Alternate Name:ACP-196Activity:Highly selective BTK inhibitorChemical Name:4-[8-Amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamideMolecular Weight:465.52Molecular Formula:C26H23N7O2Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Defactinib | Potent FAK inhibitor
From $65.00CAS:1073154-85-4Catalog Number:10-4828Activity:Potent FAK inhibitorChemical Name:N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamideMolecular Weight:510.50Molecular Formula:C20H21F3N8O3SSolubility:Soluble in DMSO (up to at least 25mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Deucravacitinib | Allosteric TYK2 inhibitor
From $100.00CAS:1609392-27-9Catalog Number:10-4756Activity:Allosteric TYK2 inhibitorChemical Names:6-(Cyclopropanecarbonylamino)-4-[2-methoxy-3-(1-methyl-1,2,4-triazol-3-yl)anilino]-N-(trideuteriomethyl)pyridazine-3-carboxamideAlternate Name:BMS-986165Molecular Weight:425.47Molecular Formula:C20H19D3N8O3Solubility:Soluble in DMSO (25 mg/ml with warming); ethanol (20 mg/ml)Physical Properties:White to off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
