Bioprocessing

Bioprocessing is the generation of products—including biotherapeutics (e.g. proteins, drugs, stem cells) —using cellular organelles, cells, viruses, or whole organisms. Various small molecules can be utilized to optimize many stages of the process, including defined medium design, feed/supplement selection, expression host selection, lead candidate production, process optimization, scaleup, and validation. These include modulators of glycosylation, cell growth, protease activity, and cellular transport to enhance production and quality.

Antibiotics & Antifungals

  • Actinomycin D | Transcription inhibitor
    CAS:
    50-76-0
    Catalog Number:
    10-2054
    Activity:
    Transcription inhibitor
    Molecular Weight:
    1255.42
    Molecular Formula:
    C62H86N12O16
    Solubility:
    Soluble in DMSO (50 mg/ml).
    Physical Properties:
    Orange-red solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Protect from exposure to light and moisture. Solutions are not stable and must be made fresh and used within one working day. Do not store solutions.
    Shipping Code:
    RT
  • Puromycin | Translation inhibitor
    CAS:
    58-58-2
    Catalog Number:
    10-2100
    Activity:
    Translation inhibitor
    Chemical Name:
    (S)-3′-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]-amino]-3′-deoxy-N,N-dimethyl-adenosine dihydrochloride
    Molecular Weight:
    544.43
    Molecular Formula:
    C22H29N7O5 2HCl
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Blasticidin S HCl | Antibiotic selection agent
    CAS:
    3513-03-9
    Catalog Number:
    10-2830
    Activity:
    Blasticidin S HCl
    Chemical Name:
    (S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid hydrochloride
    Molecular Weight:
    458.90
    Molecular Formula:
    C17H26N8O5 &bul; HCl
    Solubility:
    Soluble in Water (greater than 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Cycloheximide | Protein synthesis inhibitor
    CAS:
    66-81-9
    Catalog Number:
    10-1117
    Activity:
    Protein synthesis inhibitor
    Alternate Names:
    U-4527
    Chemical Name:
    4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
    Molecular Weight:
    281.35
    Molecular Formula:
    C15H23NO4
    Solubility:
    Soluble in Ethanol (up to 14 mg/ml) or in Water (up to 7 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    96% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in ethanol or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Doxycycline monohydrate | Broad spectrum antibiotic
    CAS:
    17086-28-1
    Catalog Number:
    10-3765

Apoptosis & Autophagy Modulators

  • Forskolin | Adenylate cyclase activator
    CAS:
    66575-29-9
    Catalog Number:
    10-2073
    Activity:
    Adenylate cyclase activator
    Chemical Name:
    7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one
    Molecular Weight:
    410.51
    Molecular Formula:
    C22H34O7
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
  • Bafilomycin A1 | Vacuolar H+ ATPase inhibitor
    CAS:
    88899-55-2
    Catalog Number:
    10-2060
    Activity:
    Vascular H+-ATPase inhibitor
    Molecular Weight:
    622.84
    Molecular Formula:
    C35H58O9
    Solubility:
    Soluble in DMSO (up to 5 mg/ml, with warming).
    Physical Properties:
    Off-white or yellow film
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • IBMX | PDE inhibitor
    CAS:
    28822-58-4
    Catalog Number:
    10-1008
    Activity:
    PDE inhibitor
    Alternate Names:
    3-Isobutyl-1-methylxanthine
    Chemical Name:
    3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
    Molecular Weight:
    222.25
    Molecular Formula:
    C10H14N4O2
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Rapamycin | mTOR inhibitor
    CAS:
    53123-88-9
    Catalog Number:
    10-1104
    Activity:
    mTOR inhibitor
    Alternate Names:
    Sirolimus
    Molecular Weight:
    914.17
    Molecular Formula:
    C51H79NO13
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 90 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years  from date of purchase as supplied.  Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
  • Concanamycin A | V-ATPase inhibitor
    CAS:
    80890-47-7
    Catalog Number:
    10-2905
    Activity:
    V-ATPase inhibitor
    Alternate Name:
    Folimycin
    Molecular Weight:
    866.09
    Molecular Formula:
    C46H75NO14
    Solubility:
    Soluble in DMSO
    Physical Properties:
    White solid or lyophilized solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT

Cell Cycle & Growth Modulators

  • Mitomycin C | DNA crosslinking and damaging agent
    CAS:
    50-07-7
    Catalog Number:
    10-1170
    Activity:
    DNA crosslinking and damaging agent
    Chemical Name:
    Natural fermentation product from Streptomyces sp.
    Molecular Weight:
    334.33
    Molecular Formula:
    C15H18N4O5
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or in Water (up to 1 mg/ml).
    Physical Properties:
    Blue-violet solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. Storing aqueous solutions is not recommended.
    Shipping Code:
    RT
  • Aphidicolin | DNA polymerase inhibitor
    CAS:
    38966-21-1
    Catalog Number:
    10-2058
    Activity:
    DNA polymerase inhibitor
    Chemical Name:
    (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol
    Molecular Weight:
    338.48
    Molecular Formula:
    C20H34O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 1 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
  • Prostaglandin E2 | Prostaglandin E (EP) receptor agonist
    CAS:
    363-24-6
    Catalog Number:
    10-1358
    Activity:
    Prostaglandin E (EP) receptor agonist
    Alternate Names:
    Dinoprost; PGE2
    Chemical Name:
    (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid
    Molecular Weight:
    352.47
    Molecular Formula:
    C20H32O5
    Solubility:
    Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (greater than 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    Blue Ice
  • 7-Aminoactinomycin D | Fluorescent DNA Probe
    CAS:
    7240-37-1
    Catalog Number:
    10-2053
    Activity:
    Fluorescent DNA probe
    Molecular Weight:
    1270.42
    Molecular Formula:
    C62H87N13O16
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Purple solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions should be made fresh daily.
    Shipping Code:
    RT
  • 7α-Hydroxycholesterol | Bile acid precursor
    CAS:
    566-26-7
    Catalog Number:
    10-4538
    Activity:
    Bile acid precursor
    Chemical Name:
    5-Cholesten-3β, 7α-diol
    Molecular Weight:
    402.66
    Molecular Formula:
    C27H46O2
    Solubility:
    Soluble in DMSO or in Ethanol.
    Physical Properties:
    White or pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT

Cofactors and Coenzymes

  • Acetyl-Coenzyme A 3Li | Acetylation and fatty acid biosynthesis cofactor
    CAS:
    75520-41-1
    Catalog Number:
    10-5384
    Activity:
    Cofactor for cellular metabolism/Acetyl donor
    Chemical Name:

    Acetyl-CoA

    Molecular Weight:
    881.42
    Molecular Formula:
    C23H35Li3N7O17P3S·3H2O
    Solubility:
    Soluble in water (10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    90% (enzymatic)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied. Solutions in water may be stored at -20°C for up to 2 weeks.
    Shipping Code:
    Blue Ice
  • Nicotinamide | SIRT1 inhibitor/essential nutrient
    CAS:
    98-92-0
    Catalog Number:
    10-2840
    Activity:
    SIRT1 inhibitor/essential nutrient
    Chemical Names:
    Pyridine-3-carboxylic acid amide; Nicotinic acid amide; Niacinamide; Vitamin B3
    Molecular Weight:
    122.13
    Molecular Formula:
    C6H6N2O
    Solubility:
    Soluble in DMSO (50 mg/ml); water (50 ml)
    Physical Properties:
    White solid
    Purity:
    >99% HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Nocardamine | Iron chelator/Ferroptosis inhibitor
    CAS:
    26605-16-3
    Catalog Number:
    10-2775
    Activity:
    Iron chelator/Ferroptosis inhibitor
    Chemical Names:
    1,12,23-Trihydroxy-1,6,12,17,23,28-hexazacyclotritriacontane-2,5,13,16,24,27-hexone
    Alternate Name:
    Desferrioxamine E
    Molecular Weight:
    600.71
    Molecular Formula:
    C27H48N6O9
    Solubility:
    Soluble in DMSO (5 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT

Glycosylation Inhibitors

  • Dexamethasone | Apoptosis inducing glucocorticoid
    CAS:
    50-02-2
    Catalog Number:
    10-1134
    Activity:
    Apoptosis inducing glucocorticoid
    Chemical Name:
    (11α,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
    Molecular Weight:
    392.46
    Molecular Formula:
    C22H29FO5
    Solubility:
    Soluble in DMSO (up to 40 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
    Shipping Code:
    RT
  • Kifunensine | Mannosidase inhibitor
    CAS:
    109944-15-2
    Catalog Number:
    10-2860
    Activity:
    Mannosidase inhibitor
    Chemical Name:
    (5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione
    Alternate Names:
    FR-900494
    Molecular Weight:
    232.19
    Molecular Formula:
    C8H12N2O6
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Monensin Na | Golgi transport inhibitor
    CAS:
    22373-78-0
    Catalog Number:
    10-2659
    Activity:
    Golgi transport inhibitor
    Chemical Names:
    2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid, sodium salt
    Alternate Name:
    NSC-343257
    Molecular Weight:
    692.86
    Molecular Formula:
    C36H61O11·Na
    Solubility:
    Soluble in DMSO (25 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    90-95% TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Conduritol B epoxide | Glycosidase inhibitor
    CAS:
    6090-95-5
    Catalog Number:
    10-1172
    Activity:
    β-Glycosidase inhibitor
    Alternate Names:
    CBE
    Chemical Name:
    D,L-1,2-Anhydro-myo-inositol
    Molecular Weight:
    162.14
    Molecular Formula:
    C6H10O5
    Solubility:
    Soluble in Water (up to 25 mg/ml) or in DMSO
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Compound is hygroscopic, protect from moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Castanospermine | Glucosidase inhibitor
    CAS:
    79831-76-8
    Catalog Number:
    10-1132
    Activity:
    Glycosidase inhibitor
    Chemical Name:
    (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine
    Molecular Weight:
    189.21
    Molecular Formula:
    C8H15NO4
    Solubility:
    Soluble in Water (up to 25 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT

Protease & Phosphatase Inhibitors

  • Bortezomib | Proteasome inhibitor
    CAS:
    179324-69-7
    Catalog Number:
    10-2120
    Activity:
    Proteasome inhibitor
    Alternate Names:
    MG-341, PS-341
    Chemical Name:
    N-(2-Pyrazine)carbonyl-L-phenylalanine-L-leucine boronic acid
    Molecular Weight:
    384.25
    Molecular Formula:
    C19H25BN4O4
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 35 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • Okadaic acid | Protein phosphatase inhibitor
    CAS:
    78111-17-8
    Catalog Number:
    10-2091
    Activity:
    Protein phosphatase inhibitor
    Source:
    Isolated from marine dinoflagellates
    Molecular Weight:
    805.00
    Molecular Formula:
    C44H68O13
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • MG-132 | Proteasome inhibitor
    CAS:
    133407-82-6
    Catalog Number:
    10-1309
    Activity:
    Proteasome inhibitor
    Alternate Names:
    Z-Leu-Leu-Leu-CHO
    Chemical Name:
    N-(Benzyloxycarbonyl)leucinylleucinylleucinal
    Molecular Weight:
    475.63
    Molecular Formula:
    C26H41N3O5
    Solubility:
    Soluble in DMSO (up to 45 mg/ml), in DMF (up to 45 mg/ml), or in Ethanol (up to 45 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, DMF or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
  • Leupeptin hemisulfate | Trypsin-like cysteine protease inhibitor
    CAS:
    103476-89-7
    Catalog Number:
    10-1346
    Activity:
    Trypsin-like cysteine protease inhibitor
    Alternate Names:
    Ac-Leu-Leu-Arg-CHO, hemisulfate
    Molecular Weight:
    475.59
    Molecular Formula:
    C20H38N6O4 &bul; 1/2H2SO4
    Solubility:
    Soluble in Water (up to 50 mg/ml). Also soluble in ethanol and methanol
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied Solutions in distilled water, ethanol or methanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • E-64 | Cysteine protease inhibitor
    CAS:
    66701-25-5
    Catalog Number:
    10-1345
    Activity:
    Cysteine protease inhibitor
    Chemical Name:
    (2S,3S)-trans-Epoxy succinyl-L-leucylamido-(4-guanidino)butane
    Molecular Weight:
    357.41
    Molecular Formula:
    C15H27N5O5
    Solubility:
    Soluble in a 1:1 mixture of Ethanol and Water (up to 20 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in 1:1 ethanol/water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT

Protein Expression Modulators

  • Brefeldin A | Inhibits intracellular transport
    CAS:
    20350-15-6
    Catalog Number:
    10-1071
    Activity:
    Inhibits intracellular transport
    Alternate Names:
    Fermentation product from Penicillium brefeldianum
    Molecular Weight:
    280.37
    Molecular Formula:
    C16H24O4
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Trichostatin A | HDAC inhibitor
    CAS:
    58880-19-6
    Catalog Number:
    10-2110
    Activity:
    HDAC inhibitor
    Alternate Names:
    TSA
    Chemical Name:
    (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
    Molecular Weight:
    302.38
    Molecular Formula:
    C17H22N2O3
    Solubility:
    Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 3 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • SAHA | HDAC inhibitor
    CAS:
    149647-78-9
    Catalog Number:
    10-1067
    Activity:
    HDAC inhibitor
    Alternate Names:
    Vorinostat
    Chemical Name:
    Suberoylanilide-hydroxamic acid
    Molecular Weight:
    264.33
    Molecular Formula:
    C14H20N2O3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
    Shipping Code:
    RT
  • Antibiotic A-23187 | Ca²⁺ ionophore
    CAS:
    52665-69-7
    Catalog Number:
    10-2284
    Activity:
    Ca2+ ionophore
    Alternate Names:
    Calcimycin
    Molecular Weight:
    523.62
    Molecular Formula:
    C29H37N3O6
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98%
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
  • Resveratrol | Antioxidant/SIRT1 activator
    CAS:
    501-36-0
    Catalog Number:
    10-1057
    Activity:
    Antioxidant/SIRT1 activator
    Alternate Names:
    5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
    Chemical Name:
    3,4′,5-Trihydroxy-trans-stilbene
    Molecular Weight:
    228.25
    Molecular Formula:
    C14H12O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT

Selection & Amplification Reagents

  • Prostratin | Promotes neuro-regeneration
    CAS:
    60857-08-1
    Catalog Number:
    10-2169
    Activity:
    Promotes neuro-regeneration
    Chemical Name:
    13-O-Acetyl-12-deoxyphorbol
    Alternate Names:
    12-Deoxyphorbol 13-Acetate; dPAc
    Molecular Weight:
    390.47
    Molecular Formula:
    C22H30O6
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
  • Colchicine | Microtubule depolymerizer
    CAS:
    64-86-8
    Catalog Number:
    10-2310
    Activity:
    Microtubule depolymerizing agent
    Chemical Name:
    (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
    Molecular Weight:
    399.45
    Molecular Formula:
    C22H25NO6
    Solubility:
    Soluble in DMSO (up to 25 mg/ml), in Water (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White to pale-yellow solid
    Purity:
    99% by TLC/HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, ethanol or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • Ouabain | Na+/K+ ATPase inhibitor
    CAS:
    11018-89-6
    Catalog Number:
    10-1248
    Activity:
    Na+/K+ ATPase inhibitor
    Chemical Name:
    3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11_,14,19-pentahydoxycard-20(22)-enolide octahydrate
    Molecular Weight:
    728.79
    Molecular Formula:
    C29H44O12·8(H2O)
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Hypoxanthine | Nutrient additive for cell culture
    CAS:
    68-94-0
    Catalog Number:
    10-5380
    Activity:
    Nutrient additive for cell culture
    Chemical Names:
    1,9-Dihydro-6H-purin-6-one; 6-Hydroxypurine
    Molecular Weight:
    136.11
    Molecular Formula:
    C5H4N4O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
  • Methotrexate | Dihydrofolate reductase inhibitor
    CAS:
    133073-73-1
    Catalog Number:
    10-1260
    Activity:
    Dihydrofolate reductase inhibitor
    Chemical Names:
    N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid; Amethopterin; CL-14377; NSC740
    Molecular Weight:
    683.63
    Molecular Formula:
    C20H22N8O5·XH2O
    Solubility:
    Soluble in DMSO (45 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT

Stem Cell Modulators

  • Forskolin | Adenylate cyclase activator
    CAS:
    66575-29-9
    Catalog Number:
    10-2073
    Activity:
    Adenylate cyclase activator
    Chemical Name:
    7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one
    Molecular Weight:
    410.51
    Molecular Formula:
    C22H34O7
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
    Shipping Code:
    RT
  • A 83-01 | ALK inhibitor
    CAS:
    909910-43-6
    Catalog Number:
    10-1327
    Activity:
    ALK inhibitor
    Chemical Name:
    3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
    Molecular Weight:
    421.53
    Molecular Formula:
    C25H19N5S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Light yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
  • Y-27632 dihydrochloride | ROCK family kinase inhibitor
    CAS:
    129830-38-2
    Catalog Number:
    10-2301
    Activity:
    ROCK family kinase inhibitor
    Chemical Name:
    (R)-(+)-trans-4-(1-Aminoethyl)-N-(-4-pyridyl)cyclohexanecarboxamide dihydrochloride
    Molecular Weight:
    320.26
    Molecular Formula:
    C14H21N3O 2HCl
    Solubility:
    Soluble in DMSO (>100 mg/ml) or in water (>75 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • PD 325901 MEK inhibitor
    CAS:
    391210-10-9
    Catalog Number:
    10-2161
    Activity:
    MEK inhibitor
    Chemical Name:
    N-[(2R(-))-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
    Molecular Weight:
    482.2
    Molecular Formula:
    C16H14F3IN2O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
  • Dorsomorphin | AMPK inhibitor
    CAS:
    866405-64-3
    Catalog Number:
    10-1029
    Activity:
    AMPK inhibitor
    Alternate Names:
    Compound C
    Chemical Name:
    6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine
    Molecular Weight:
    399.49
    Molecular Formula:
    C24H25N5O
    Solubility:
    Soluble in DMSO (up to 3 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT