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Tumor Microenvironment

  • PLX5622 | Highly selective CSF1R inhibitor

    CAS:
    1303420-67-8
    Catalog Number:
    10-4726
    Activity:
    Highly selective CSF1R inhibitor
    Chemical Names:
    6-Fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)methyl]pyridine-2-amine
    Molecular Weight:
    395.41
    Molecular Formula:
    C21H19F2N5O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
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  • Preladenant | Potent and selective adenosine A2A antagonist

    CAS:
    377727-87-2
    Catalog Number:
    10-4102
    Chemical Name:
    4-(Furan-2-yl)-10-[2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]ethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
    Alternate Name:
    SCH 420814
    Molecular Weight:
    503.57
    Molecular Formula:
    C29H29N9O3
    Solubility:
    Soluble in DMSO (up to 5 mg/ml with warming).
    Physical Properties:
    Beige solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $70.00
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  • Reparixin | CXCR 1/2 allosteric antagonist

    CAS:
    266359-83-5
    Catalog Number:
    10-2527
    Activity:
    CXCR 1/2 allosteric antagonist
    Chemical Name:
    αR-Methyl-4-(2-methylpropyl)-N-(methylsulfonyl)-benzeneacetamide
    Alternate Names:
    DF 1681Y; Repertaxin
    Molecular Weight:
    283.39
    Molecular Formula:
    C14H21NO3S
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $52.00
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  • Resiquimod chemical structure

    Resiquimod | TLR7/8 agonist / Immune adjuvant

    CAS:
    144875-48-9
    Catalog Number:
    10-2733
    Activity:
    TLR7/8 agonist / Immune adjuvant
    Chemical Name:
    1-[4-Amino-2-ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
    Alternate Names:
    R848
    Molecular Weight:
    314.39
    Molecular Formula:
    C17H22N4O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $65.00
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  • SAHA | HDAC inhibitor

    CAS:
    149647-78-9
    Catalog Number:
    10-1067
    Activity:
    HDAC inhibitor
    Alternate Names:
    Vorinostat
    Chemical Name:
    Suberoylanilide-hydroxamic acid
    Molecular Weight:
    264.33
    Molecular Formula:
    C14H20N2O3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
    Shipping Code:
    RT
    From $35.00
    View Product This product has multiple variants. The options may be chosen on the product page
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