Apoptosis

  • Crizotinib | c-MET and ALK inhibitor

    CAS:
    877399-52-5
    Catalog Number:
    10-2626
    Activity:
    c-MET and ALK inhibitor
    Chemical Name:
    3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
    Alternate Names:
    PF-02341066, PF-1066
    Molecular Weight:
    450.34
    Molecular Formula:
    C21H22Cl2FN5O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $80.00
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  • CUR 61414 | Hedgehog pathway antagonist

    CAS:
    334998-36-6
    Catalog Number:
    10-1392
    Activity:
    Hedgehog pathway antagonist
    Chemical Name:
    N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
    Molecular Weight:
    550.71
    Molecular Formula:
    C31H42N4O5
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $90.00
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  • Cytochalasin B | Actin filament disrupting agent

    CAS:
    14930-96-2
    Catalog Number:
    10-2069
    Activity:
    Actin filament disrupting agent
    Fermentation product:
    from Drechslera dematioidea
    Alternate Name:
    NSC107658; Phominone
    Molecular Weight:
    479.61
    Molecular Formula:
    C29H37NO5
    Solubility:
    Soluble in DMSO (up to 5 mg/ml); Ethanol (10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • Dasatinib | Src and Bcr/Abl inhibitor

    CAS:
    302962-49-8
    Catalog Number:
    10-2126
    Activity:
    Src and Bcr/Abl inhibitor
    Alternate Names:
    BMS-354825
    Chemical Name:
    N-(2-Chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino) thiazole-5-carboxamide
    Molecular Weight:
    488.01
    Molecular Formula:
    C22H26ClN7O2S
    Solubility:
    Soluble in DMSO (up to 200 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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  • Daunorubicin HCl | DNA Damaging Agent / Anticancer Agent

    CAS:
    23541-50-6
    Catalog Number:
    10-2429
    Activity:
    DNA Damaging Agent / Anticancer agent
    Alternate Names:
    Daunomycin; rubidomycin; RP-13057
    Molecular Weight:
    536.98
    Molecular Formula:
    C27H39NO10 • HCl
    Solubility:
    Soluble in water (up to 25 mg/ml)
    Physical Properties:
    Red solid
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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