Apoptosis

  • PLX4032 | BRAF inhibitor

    CAS:
    918504-65-1
    Catalog Number:
    10-2928
    Activity:
    BRAF inhibitor
    Chemical Name:
    N-[3-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
    Alternate Names:
    Vemurafenib, R7204, Ro 51-85426
    Molecular Weight:
    489.92
    Molecular Formula:
    C23H18ClF2N3O3S
    Solubility:
    Soluble in DMSO (up to 100 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Ponasterone A | Insect steroid hormone

    CAS:
    13408-56-5
    Catalog Number:
    10-1404
    Activity:
    Insect steroid hormone
    Chemical Names:
    (5β)-2β,3β,14,20,22R-pentahydroxy-cholest-7-en-6-one
    Alternate Name:
    25-Deoxy-2-hydroxyecdysone; 25-deoxyecdysterone
    Molecular Weight:
    464.64
    Molecular Formula:
    C27H44O6
    Solubility:
    Soluble in DMSO (30 mg/ml); Ethanol (5 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >97% HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • PRIMA-1(MET) | Reactivates mutant p53

    CAS:
    5291-32-7
    Catalog Number:
    10-4175
    Activity:
    Reactivates mutant p53
    Chemical Name:
    2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
    Alternate Names:
    APR-246
    Molecular Weight:
    199.25
    Molecular Formula:
    C10H17NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    95%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Purvalanol A | CDK inhibitor

    CAS:
    212844-53-6
    Catalog Number:
    10-2868
    Activity:
    CDK Inhibitor
    Chemical Name:
    (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol
    Alternate Names:
    NG-60
    Molecular Weight:
    388.89
    Molecular Formula:
    C19H25ClN6O
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    Pale green solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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  • RITA | p53 Activator

    CAS:
    213261-59-7
    Catalog Number:
    10-3385
    Activity:
    p53 Activator
    Chemical Names:
    5,5′-(2,5-Furandiyl)bis-2-thiophenemethanol;
    NSC 652287
    Molecular Weight:
    292.37
    Molecular Formula:
    C14H12O3S2
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page
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