Retinoic acid | Retinoid RAR agonist
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 50 mg | $30.00 | ||
| 500 mg | $60.00 |
all-trans-Retinoic acid (302-79-4) a metabolite of Vitamin A, is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells.1 Retinoic acid promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.2-4
References/Citations:
1) Allenby (1993), Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acid; Proc. Natl. Acad. Sci. USA, 90 30
2) Dani et . (1997) Differentiation of embryonic stem cells into adipocytes in vitro; J. Cell Sci. 110 1279
3) Hu (2009) Differentiation Of Spinal Motor Neurons From Pluripotent Human Stem Cells; Nat. Protoc., 4 1295
4) Sasai (2002) Generation of dopaminergic neurons from embryonic stem cells J. Neurol., 249 II 41
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
all-trans-Retinoic acid (302-79-4) a metabolite of Vitamin A, is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells.1 Retinoic acid promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.2-4
References/Citations:
1) Allenby (1993), Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acid; Proc. Natl. Acad. Sci. USA, 90 30
2) Dani et . (1997) Differentiation of embryonic stem cells into adipocytes in vitro; J. Cell Sci. 110 1279
3) Hu (2009) Differentiation Of Spinal Motor Neurons From Pluripotent Human Stem Cells; Nat. Protoc., 4 1295
4) Sasai (2002) Generation of dopaminergic neurons from embryonic stem cells J. Neurol., 249 II 41
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