Ritonavir | HIV1/2 protease inhibitor

CAS:
155213-67-5
Catalog Number:
10-4484
Activity:
HIV 1/2 protease inhibitor
Chemical Name:
1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-2-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
Molecular Weight:
720.95
Molecular Formula:
C37H48N5O5S2
Solubility:
Soluble in DMSO (up to 12 mg/ml with warming) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Shipping Code:
RT

Available Options

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20 mg$40.00
100 mg$150.00
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Ritonavir (155213-67-5) is a clinically useful HIV-1/HIV-2 protease inhibitor.1 Potent inhibitor of cytochrome P450 3A4.2,3

References/Citations:

1) Lea and Faulds (2018) Ritonavir; Drugs 52 541
2) Koudriakova et al. (1998) Metabolism of the Human Immunodeficiency Virus Protease Inhibitors Indinavir and Ritonavir by Human Intestinal Microsomes and Expressed Cytochrome P4503A4/3A5: Mechanism-Based Inactivation of Cytochrome P3503A by Ritonavir; Drug Metab. Dispos. 26 552
3) Rock et al. (2014) Characterization of Ritonavir-Mediated Inactivation of Cytochrome P450 3A4; Mol. Pharmacol. 86 665

CAS:
155213-67-5
Catalog Number:
10-4484
Activity:
HIV 1/2 protease inhibitor
Chemical Name:
1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-2-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
Molecular Weight:
720.95
Molecular Formula:
C37H48N5O5S2
Solubility:
Soluble in DMSO (up to 12 mg/ml with warming) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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