RO 20-1724 | PDE4 inhibitor

CAS:
29925-17-5
Catalog Number:
10-1014
Activity:
PDE4 inhibitor
Chemical Name:
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
Molecular Weight:
278.35
Molecular Formula:
C15H22N2O3
Solubility:
Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 40 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
50 mg$45.00
250 mg$150.00

RO 20-1724 (29925-17-5) is a selective inhibitor of cAMP-specific phosphodiesterase (PDE4), IC50 = 0.2 μM. Displays anti-inflammatory activity. Cell permeable

References/Citations:

1) Soderling et al. (1998), Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase; Proc. Natl. Acad. Sci. USA, 95 8991
2) Nicholson et al. (1991), Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes; Trends Pharmacol. Sci., 12 19

CAS:
29925-17-5
Catalog Number:
10-1014
Activity:
PDE4 inhibitor
Chemical Name:
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
Molecular Weight:
278.35
Molecular Formula:
C15H22N2O3
Solubility:
Soluble in DMSO (up to 200 mg/ml) or in Ethanol (up to 40 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 6 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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