S-Farnesyl-L-cysteine methyl ester | Multidrug resistance transporter activator

CAS:
125741-64-2
Catalog Number:
10-4608
Activity:
Multidrug resistance transporter activator
Chemical Name:
(2R)-2-Amino-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylpropanoic acid methyl ester
Molecular Weight:
339.54
Molecular Formula:
C19H33NO2S
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml)
Physical Properties:
Pale yellow oil
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$70.00
25 mg$275.00

S-Farnesyl-L-cysteine methyl ester (125741-64-2) stimulates multidrug resistance transporter ATPase activity (4-5 fold at 10-20 µM) and competes for drug binding.1 It modifies the carboxyl terminus of the Saccharomyces cerevisiae RAS2 protein.2

References/Citations:

1) Zhang et al. (1994), Interaction of prenylcysteine methyl esters with multidrug resistance transporter; J. Biol. Chem. 269 15973
2) Stimmel et al. (1990), Evidence for an S-farnesylcysteine methyl ester at the carboxyl terminus of the Saccharomyces cerevisiae RSA2 protein; Biochemistry 29 9651

CAS:
125741-64-2
Catalog Number:
10-4608
Activity:
Multidrug resistance transporter activator
Chemical Name:
(2R)-2-Amino-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylpropanoic acid methyl ester
Molecular Weight:
339.54
Molecular Formula:
C19H33NO2S
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml)
Physical Properties:
Pale yellow oil
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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