SBI-0206965 | ULK1 inhibitor
NMR (Conforms)
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $65.00 | ||
| 25 mg | $260.00 |
SBI-0206965 (1884220-36-3) is a potent and selective inhibitor of the autophagy kinase ULK-1, IC50=108 and 711 nM for ULK1 and 2 respectively.1 Suppresses autophagy induced by mTOR inhibitors and thus synergizes with mTOR inhibitors to induce apoptosis and cell death in tumor cells.1
References/Citations:
1) Egan et al. (2015), Small Molecules Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates; Mol. Cell, 59 285
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
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SBI-0206965 (1884220-36-3) is a potent and selective inhibitor of the autophagy kinase ULK-1, IC50=108 and 711 nM for ULK1 and 2 respectively.1 Suppresses autophagy induced by mTOR inhibitors and thus synergizes with mTOR inhibitors to induce apoptosis and cell death in tumor cells.1
References/Citations:
1) Egan et al. (2015), Small Molecules Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates; Mol. Cell, 59 285
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