Size: | Price | Quantity | |
---|---|---|---|
5 mg | $52.00 | ||
25 mg | $208.00 |
SCH-202676 (265980-25-4) is a reversible inhibitor of both agonist and antagonist binding to G protein-coupled receptors (GPCRs).1 IC50‘s = 0.1-1.7 μM for nine GPCRs.1 Modification of GPCRs is accomplished via sulfhydryl modification.2,3
References/Citations:
1) Fawzi et al. (2001), SCH-202676: an allosteric modulator of both agonist and antagonist binding to G protein-coupled receptors; Mol.Pharmacol. 59 30
2) Lewandowicz et al. (2006), The allosteric modulator SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms; Br. J. Pharmacol. 147 422
3) Goblyos et al. (2005), Synthesis and biological evaluation of a new series of 2,3,5-substituted[1,2,4]-thiadiazoles as modulators of adenosine A1 receptors and their molecular mechanism of action; J. Med. Chem., 48 1145
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
SCH-202676 (265980-25-4) is a reversible inhibitor of both agonist and antagonist binding to G protein-coupled receptors (GPCRs).1 IC50‘s = 0.1-1.7 μM for nine GPCRs.1 Modification of GPCRs is accomplished via sulfhydryl modification.2,3
References/Citations:
1) Fawzi et al. (2001), SCH-202676: an allosteric modulator of both agonist and antagonist binding to G protein-coupled receptors; Mol.Pharmacol. 59 30
2) Lewandowicz et al. (2006), The allosteric modulator SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms; Br. J. Pharmacol. 147 422
3) Goblyos et al. (2005), Synthesis and biological evaluation of a new series of 2,3,5-substituted[1,2,4]-thiadiazoles as modulators of adenosine A1 receptors and their molecular mechanism of action; J. Med. Chem., 48 1145
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
For Postdoc
Customers!
Website Created by Advanta Advertising LLC.