SGC707 | PRMT3 inhibitor

CAS:
1687736-54-4
Catalog Number:
10-1610
Activity:
PRMT3 inhibitor
Chemical Name:
1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea
Molecular Weight:
298.34
Molecular Formula:
C16H18N4O2
Solubility:
Soluble in DMSO (up to 35 mg/ml)
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$65.00
25 mg$260.00

SGC707 (1687736-54-4) is a potent (IC50 = 31 nM) and selective allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).1  Selective against 31 other methyltransferases. An extremely useful probe for investigating the role of PRMT3 in normal and pathophysiology. Cell permeable and active in vivo.

References/Citations:

1) Kaniskan et al. (2015), A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3); Angew. Chem. Int. Ed. Engl., 54 5166

CAS:
1687736-54-4
Catalog Number:
10-1610
Activity:
PRMT3 inhibitor
Chemical Name:
1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea
Molecular Weight:
298.34
Molecular Formula:
C16H18N4O2
Solubility:
Soluble in DMSO (up to 35 mg/ml)
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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