SMER3 | E3 Ubiquitin ligase inhibitor

CAS:
67200-34-4
Catalog Number:
10-1356
Activity:
E3 Ubiquitin ligase inhibitor
Chemical Name:
9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Molecular Weight:
224.18
Molecular Formula:
C11H4N4O2S
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Available Options

size :PriceQuantity 
5 mg$60.00
25 mg$170.00

SMER3 ( 67200-34-4; Small Molecule Enhancer of Rapamycin 3) is a specific inhibitor if the ubiquitin E3 ligase SCFMET30 both in vitro and in vivo.

References/Citations:

1) Aghajanyy et al. (2010), Chemical genetics of TOR identifies an SCF family E3 ubiquitin ligase inhibitor; Nat. Biotechnol., 28 738

CAS:
67200-34-4
Catalog Number:
10-1356
Activity:
E3 Ubiquitin ligase inhibitor
Chemical Name:
9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Molecular Weight:
224.18
Molecular Formula:
C11H4N4O2S
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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