SR-3576 | JNK3 inhibitor

CAS:
1164153-22-3
Catalog Number:
10-1498
Activity:
JNK3 inhibitor
Chemical Name:
3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide
Molecular Weight:
501.53
Molecular Formula:
C27H27N5O5
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$100.00
25 mg$400.00

SR-3576 (1164153-22-3) is a potent and selective JNK3 inhibitor. IC50 = 7nM and >2800-fold selective over p38.1 Cell permeable.

References/Citations:

1) Kamenecka et al. (2009), Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38; J. Biol. Chem., 284 12853

CAS:
1164153-22-3
Catalog Number:
10-1498
Activity:
JNK3 inhibitor
Chemical Name:
3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide
Molecular Weight:
501.53
Molecular Formula:
C27H27N5O5
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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