Src-I1 | Src kinase inhibitor

CAS:
179248-59-0
Catalog Number:
10-1020
Activity:
Src kinase inhibitor
Chemical Name:
6,7-Dimethoxy-N-(4-Phenoxyphenyl)-4-quinazolinamine
Molecular Weight:
373.41
Molecular Formula:
C22H19N3O3
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
5 mg$60.00
25 mg$240.00

Src-I1 (179248-59-0) is a potent and competitive dual site (ATP- and peptide-binding) Src kinase inhibitor (IC50‘s = 44 nM for Src and 88 nM for Lck). Src-I1 also inhibits VEGFR2 (IC50 = 320 nM).

References/Citations:

1) Tian et al. (2001) Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines; Biochem. 40 7084
2) Bain et al. (2007) The selectivity of protein kinase inhibitors: a further update; Biochem. J. 408 297

CAS:
179248-59-0
Catalog Number:
10-1020
Activity:
Src kinase inhibitor
Chemical Name:
6,7-Dimethoxy-N-(4-Phenoxyphenyl)-4-quinazolinamine
Molecular Weight:
373.41
Molecular Formula:
C22H19N3O3
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

20% OFF

For Postdoc
Customers!