Stauprimide | Primes stem cells for differentiation
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $85.00 | ||
| 5 mg | $245.00 |
Stauprimide (154589-96-5) dramatically primes embryonic stem cells for differentiation.1,2 Its molecular target is NME2, a c-Myc-activating transcription factor. Stauprimide inhibits nuclear localization of NME2 thereby downregulating c-Myc.3
References/Citations:
1) Zhu et al. (2009), A small molecule primes embryonic stem cells for differentiation; Cell Stem Cell, 4 416
2) Zaret et al. (2009), Using small molecules to great effect in stem cell differentiation; Cell Stem Cell, 4 373
3) Bouvard et al. (2017) Small molecule selectively suppresses MYC transcription in cancer cells; Proc. Natl. Acad. Sci. USA 114 3497
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Stauprimide (154589-96-5) dramatically primes embryonic stem cells for differentiation.1,2 Its molecular target is NME2, a c-Myc-activating transcription factor. Stauprimide inhibits nuclear localization of NME2 thereby downregulating c-Myc.3
References/Citations:
1) Zhu et al. (2009), A small molecule primes embryonic stem cells for differentiation; Cell Stem Cell, 4 416
2) Zaret et al. (2009), Using small molecules to great effect in stem cell differentiation; Cell Stem Cell, 4 373
3) Bouvard et al. (2017) Small molecule selectively suppresses MYC transcription in cancer cells; Proc. Natl. Acad. Sci. USA 114 3497
Related products
-
Dexamethasone | Apoptosis inducing glucocorticoid
From $60.00CAS:50-02-2Catalog Number:10-1134Activity:Apoptosis inducing glucocorticoidChemical Name:(11α,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dioneMolecular Weight:392.46Molecular Formula:C22H29FO5Solubility:Soluble in DMSO (up to 40 mg/ml).Physical Properties:White solidPurity:98%
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 monthsShipping Code:RT -
5-Azacytidine | DNA hypomethylation agent
From $20.00CAS:320-67-2Catalog Number:10-1267Activity:DNA hypomethylation agentAlternate Names:Ladakamycin; U-18496; NSC-102816; AzaCChemical Name:4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-oneMolecular Weight:244.21Molecular Formula:C8H12N4O5Solubility:Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
Dorsomorphin | AMPK inhibitor
From $60.00CAS:866405-64-3Catalog Number:10-1029Activity:AMPK inhibitorAlternate Names:Compound CChemical Name:6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidineMolecular Weight:399.49Molecular Formula:C24H25N5OSolubility:Soluble in DMSO (up to 3 mg/ml).Physical Properties:Pale yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
