Stauprimide | Primes stem cells for differentiation
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $85.00 | ||
| 5 mg | $245.00 |
Stauprimide (154589-96-5) dramatically primes embryonic stem cells for differentiation.1,2 Its molecular target is NME2, a c-Myc-activating transcription factor. Stauprimide inhibits nuclear localization of NME2 thereby downregulating c-Myc.3
References/Citations:
1) Zhu et al. (2009), A small molecule primes embryonic stem cells for differentiation; Cell Stem Cell, 4 416
2) Zaret et al. (2009), Using small molecules to great effect in stem cell differentiation; Cell Stem Cell, 4 373
3) Bouvard et al. (2017) Small molecule selectively suppresses MYC transcription in cancer cells; Proc. Natl. Acad. Sci. USA 114 3497
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Stauprimide (154589-96-5) dramatically primes embryonic stem cells for differentiation.1,2 Its molecular target is NME2, a c-Myc-activating transcription factor. Stauprimide inhibits nuclear localization of NME2 thereby downregulating c-Myc.3
References/Citations:
1) Zhu et al. (2009), A small molecule primes embryonic stem cells for differentiation; Cell Stem Cell, 4 416
2) Zaret et al. (2009), Using small molecules to great effect in stem cell differentiation; Cell Stem Cell, 4 373
3) Bouvard et al. (2017) Small molecule selectively suppresses MYC transcription in cancer cells; Proc. Natl. Acad. Sci. USA 114 3497
Related products
-
Reversine | Reverses differentiated cells to multipotent stem cells
From $75.00CAS:656820-32-5Catalog Number:10-1154Activity:Reverses differentiated cells to multipotent stem cellsChemical Name:2-(4-Morpholinoanilino)-6-cyclohexylaminopurineMolecular Weight:383.5Molecular Formula:C21H27N7OSolubility:Soluble in DMSO (up to 7 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 monthsShipping Code:RT -
Neuropathiazol | Induces neuronal differentiation
From $90.00CAS:880090-88-0Catalog Number:10-1291Activity:Induces neuronal differentiationChemical Name:Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoateMolecular Weight:338.43Molecular Formula:C19H18N2O2SSolubility:Soluble in DMSO (up to 10 mg/ml).Physical Properties:Off white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
ML239 | Selective cancer stem cell killer
From $65.00CAS:1378872-36-6Catalog Number:10-1417Activity:Selective cancer stem cell killerChemical Name:(2,4,6-Trichlorophenoxy)-acetic acid (1H-pyrrol-2-ylmethylene)-hydrazideMolecular Weight:346.6Molecular Formula:C13H10Cl3N3O2Solubility:Soluble in DMSO (up to 25 mg/ml), in DMF (up to 25 mg/ml), or in Ethanol (up to 25 mg/ml)Physical Properties:Beige solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO, DMF or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
