Size | Price | Quantity | |
---|---|---|---|
5mg | $70.00 | ||
25mg | $280.00 |
STF-118804 (894187-61-2) is a potent and selective next generation inhibitor of nicotinamide phosphoribosyl transferase (NAMPT), inhibiting NAD+ biosynthesis from nicotinamide.1 It reduced the viability of most B-ALL cells with high potency (low nM range), eliminates leukemia stem cells from mouse bone marrow, and induces regression of ALL xenografts.1 It induces apoptosis and reduced neuroblastoma stem cell neurosphere formation in high-risk neuroblastoma cell lines.2 STF-118804 reduces the growth of pancreatic ductal adenocarcinoma cells.3
References/Citations:
C25H23N3O4S
>98% HPLC
NMR (Conforms)
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
STF-118804 (894187-61-2) is a potent and selective next generation inhibitor of nicotinamide phosphoribosyl transferase (NAMPT), inhibiting NAD+ biosynthesis from nicotinamide.1 It reduced the viability of most B-ALL cells with high potency (low nM range), eliminates leukemia stem cells from mouse bone marrow, and induces regression of ALL xenografts.1 It induces apoptosis and reduced neuroblastoma stem cell neurosphere formation in high-risk neuroblastoma cell lines.2 STF-118804 reduces the growth of pancreatic ductal adenocarcinoma cells.3
References/Citations:
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Concentration × Volume × Molecular Weight = Mass
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