Surfactin | Lipopeptide biosurfactant

CAS:
24730-31-2
Catalog Number:
10-5131
Activity:
Lipopeptide biosurfactant
Source:
Cyclic peptide produced by Bacillus substilis
Molecular Weight:
1036.36 (based on C15 subunit)
Molecular Formula:
C53H93N7O13 (based on C15 subunit)
Solubility:
Soluble in DMSO (15 mg/ml)
Physical Properties:
White to off-white solid
Purity:
>98% TLC; HPLC shows mixture of isomers with C14 and C15 side chains predominating.1
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Available Options

Size:PriceQuantity 
1 mg$50.00
5 mg$150.00

Surfactin (24730-31-2) is a lipopeptide biosurfactant2 which displays various activities including antifungal and antibacterial as well as inhibition of fibrin clot formation3.  Selectively inhibits cytosolic PLA2 (IC50=8.5 mM) suppressing PLA2-mediated inflammatory responses.4 Induces ER stress-mediated apoptosis via IRE1-ASK1-JNK signaling in human osteosarcoma cells.5

References/Citations:

  1. Oka et al. (1993), Satisfactory separation and MS-MS spectrometry of six surfactins isolated from Bacillus substilis natto; Chem. Pharm. Bull., 41 1000
  2. Mulligan et al. (2005), Environmental applications for biosurfactants; Env. Pol., 133 183
  3. Singh and Cameotra. (2004), Potential applications of microbial surfactants in biomedical sciences; Trends Biotechnol., 22 142
  4. Kim et al. (1998), Suppression of inflammatory responses by surfactin, a selective inhibitor of platelet cytosolic phospholipase A2; Biochem. Pharmacol., 55 975
  5. Wang et al. (2022), Surfactin induces ER stress-mediated apoptosis via IRE1-ASK1-JNK signaling in human osteosarcoma; Environ. Toxicol., 37 574
CAS:
24730-31-2
Catalog Number:
10-5131
Activity:
Lipopeptide biosurfactant
Source:
Cyclic peptide produced by Bacillus substilis
Molecular Weight:
1036.36 (based on C15 subunit)
Molecular Formula:
C53H93N7O13 (based on C15 subunit)
Solubility:
Soluble in DMSO (15 mg/ml)
Physical Properties:
White to off-white solid
Purity:
>98% TLC; HPLC shows mixture of isomers with C14 and C15 side chains predominating.1
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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