T-10418 | G2A agonist
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $70.00 | ||
| 25 mg | $260.00 |
T-10418 (1608784-68-4) is a potent (EC50 = 820 nM) and selective (against 300 non-olfactory GPCRs) agonist of G2 accumulation protein (G2A; GPR132). At 100 nM, T-10418 resulted in 244% TRPV1 sensitization in mouse sensory neurons. T-10418 is an interesting new chemical tool to study G2A biology.
References/Citations:
- Hernandez-Olmos et al. (2024), Development of a Potent and Selective G2A (GPR132) Agonist; J.Med.Chem. 67 10567
C22H20N2O4
98% HPLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
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T-10418 (1608784-68-4) is a potent (EC50 = 820 nM) and selective (against 300 non-olfactory GPCRs) agonist of G2 accumulation protein (G2A; GPR132). At 100 nM, T-10418 resulted in 244% TRPV1 sensitization in mouse sensory neurons. T-10418 is an interesting new chemical tool to study G2A biology.
References/Citations:
- Hernandez-Olmos et al. (2024), Development of a Potent and Selective G2A (GPR132) Agonist; J.Med.Chem. 67 10567
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