Tianeptine sodium salt | Neuroprotective agent
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $40.00 | ||
| 50 mg | $100.00 |
Tianeptine sodium salt (30123-17-2) is a selective enhancer of serotonin uptake in the brain with no effect on noradrenalin or dopamine uptake.1 Clinically useful antidepressant.2 Displays neuroprotective effects against hypoxia in cell culture and against the deleterious effects of cytokines in vivo.3 Induces mTORC1 activation in rat hippocampal neurons and increases dendritic outgrowth, spine density and synaptic proteins.4 Attenuates LPS-evoked inflammatory activation of microglial cells in culture.5
References/Citations
1) Mennini et al. (1987), Tianeptine, a selective enhancer of serotonin uptake in rat brain; Naunyn-Schmied. Arch. Pharmacol., 336 478
2) Kato and Weitsch (1988), Neurochemical profile of tianeptine, a new antidepressant drug; Clin. Neuropharmacol., 11 S43
3) Plaisant et al. (2003), Neuroprotective properties of tianeptine: interactions with cytokines; Neuropharmacology, 44 801
4) Seo et al. (2016), Tianeptine induces mTORC1 activation in rat hippocampal neurons under toxic conditions; Psychopharmacology (Berl.), 233 2617
5) Slusarczyk et al. (2017), Anti-inflammatory properties of tianeptine on lipopolysaccharide-induced changes in microglial cells involve toll-like receptor-related pathways; J. Neurochem., 136 958
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Tianeptine sodium salt (30123-17-2) is a selective enhancer of serotonin uptake in the brain with no effect on noradrenalin or dopamine uptake.1 Clinically useful antidepressant.2 Displays neuroprotective effects against hypoxia in cell culture and against the deleterious effects of cytokines in vivo.3 Induces mTORC1 activation in rat hippocampal neurons and increases dendritic outgrowth, spine density and synaptic proteins.4 Attenuates LPS-evoked inflammatory activation of microglial cells in culture.5
References/Citations
1) Mennini et al. (1987), Tianeptine, a selective enhancer of serotonin uptake in rat brain; Naunyn-Schmied. Arch. Pharmacol., 336 478
2) Kato and Weitsch (1988), Neurochemical profile of tianeptine, a new antidepressant drug; Clin. Neuropharmacol., 11 S43
3) Plaisant et al. (2003), Neuroprotective properties of tianeptine: interactions with cytokines; Neuropharmacology, 44 801
4) Seo et al. (2016), Tianeptine induces mTORC1 activation in rat hippocampal neurons under toxic conditions; Psychopharmacology (Berl.), 233 2617
5) Slusarczyk et al. (2017), Anti-inflammatory properties of tianeptine on lipopolysaccharide-induced changes in microglial cells involve toll-like receptor-related pathways; J. Neurochem., 136 958
Related products
-
Nafamostat Mesylate | Serine protease inhibitor
From $50.00CAS:82956-11-4Catalog Number:10-1089Activity:Serine protease inhibitorAlternate Names:Futhan; FUT-175Chemical Name:6-Amidino-2-naphthyl-4-guanidinobenzoate dimesylateMolecular Weight:539.59Molecular Formula:C19H17N5O2·2CH4O3SSolubility:Soluble in Water (up to 25 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at 4°C for up to 1 month, or at -80°C for up to 6 months.Shipping Code:RT -
Simvastatin | HMG-CoA reductase inhibitor
From $50.00CAS:79902-63-9Catalog Number:10-1018Activity:HMG-CoA reductase inhibitorAlternate Names:MevinolinChemical Name:2,2-Dimethyl-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acidMolecular Weight:418.58Molecular Formula:C25H38O5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Rosiglitazone maleate | PPAR gamma agonist
From $55.00CAS:155141-29-0Catalog Number:10-1012Activity:PPARγ agonistAlternate Names:Avandia; BRL49653Chemical Name:5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione maleateMolecular Weight:357.43Molecular Formula:C18H19N3O3SSolubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 monthsShipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
