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Product Details

Triacetyl resveratrol | SIRT activator, prodrug

A resveratrol prodrug. One method for increasing the half-life of resveratrol in vivo is acetylation of the phenolic OH groups. Deacetylation takes place in vivo or in intact cells via the action of intracellular esterases releasing active resveratrol.

References/Citations

1) Hsieh et al. (2011), Control of prostate cell growth, DNA damage and repair and gene expression by resveratrol analogues, in vitro; Carcinogenesis, 32 93
2) Hsieh et al. (2011), Regulation of p53 and cell proliferation by resveratrol and it’s derivatives in breast cancer cells: an in silico and biochemical approach to targeting integrin αvβ3; Int. J. Cancer, 129 2732

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Catalog#  10-2437-0050

$55.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
42206-94-0
Catalog Number:
10-2437
Activity:
SIRT activator, prodrug
Chemical Name:
5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate
Alternate Names:
3,5,4’-Tri-O-acetylresveratrol
Molecular Weight:
364.43
Molecular Formula:
C20H28O6
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in ethanol (up to 8 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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