Triacsin C | Acyl-CoA synthase inhibitor

CAS:
76896-80-5
Catalog Number:
10-2109
Activity:
Acyl-CoA synthase inhibitor
Chemical Name:
(3E)-1-Hydroxy-3-((2E,4Z,7E)-undeca-2,4,7-triene-1-ylidene)triaz-1-ene
Molecular Weight:
207.28
Molecular Formula:
C11H17N3O
Solubility:
Supplied in solution in DMSO at a concentration of 1 mg/ml. Maximum solubility in DMSO is 25 mg/ml.
Physical Properties:
Solution in DMSO
Purity:
95% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions further diluted with DMSO may be stored at -20° for up to 2 months.
Shipping Code:
Blue Ice

Available Options

Size :PriceQuantity 
100 µg$90.00
1 mg$504.00

Triacsin C (76896-80-5) is a long-chain fatty acyl CoA synthetase inhibitor (IC50=3.6-8.7 μM).1 Inhibits mouse macrophage-derived foam cell formation2 and displays anti-atherosclerotic activity3. Cell permeable.

References/Citations:

1) Hartman et al. (1989), Triacsin C: a differential inhibitor of arachidonoyl-CoA synthetase and nonspecific long chain acyl-CoA synthetase; Prostaglandins, 37 655
2) Namatame et al. (1999), Complete inhibition of mouse macrophage-derived foam cell formation by triacsin C; J. Biochem, 125 319
3) Matsuda et al. (2008), Anti-atherosclerotic activity of triacsin C, an acyl-CoA synthetase inhibitor; J. Antibiot. (Tokyo), 61 318

CAS:
76896-80-5
Catalog Number:
10-2109
Activity:
Acyl-CoA synthase inhibitor
Chemical Name:
(3E)-1-Hydroxy-3-((2E,4Z,7E)-undeca-2,4,7-triene-1-ylidene)triaz-1-ene
Molecular Weight:
207.28
Molecular Formula:
C11H17N3O
Solubility:
Supplied in solution in DMSO at a concentration of 1 mg/ml. Maximum solubility in DMSO is 25 mg/ml.
Physical Properties:
Solution in DMSO
Purity:
95% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions further diluted with DMSO may be stored at -20° for up to 2 months.
Shipping Code:
Blue Ice

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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