Size: | Price | Quantity | |
---|---|---|---|
10 mg | $86.00 | ||
50 mg | $344.00 |
Troglitazone (97322-87-7) is a PPARγ agonist. Stimulates recruitment of transcriptional coactivators to PPARγ at 1 μM. Stimulates adipogenesis in human mesenchymal stem cells. Troglitazone induces apoptosis in a variety of tumor cells lines. Cell permeable.
References/Citations:
γ1) Kodera et al. (2000) Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators; J. Biol. Chem., 275 33201
2) Tchoukalova et al. (2000) Enhancing effect of troglitazone on porcine adipocyte differentiation in primary culture: a comparison with dexamethasone; Obes. Res., 8 664
3) Tsubouchi et al. (2000) Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis; Biochem. Biophys. Res. Commun.270
4) Wyttenbach & Kuentz (2017), Glass-forming ability of compounds in marketed amorphous drug products; Eur. J. Pharm. and Biopharm., 112 204 [Focus Citation]
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Troglitazone (97322-87-7) is a PPARγ agonist. Stimulates recruitment of transcriptional coactivators to PPARγ at 1 μM. Stimulates adipogenesis in human mesenchymal stem cells. Troglitazone induces apoptosis in a variety of tumor cells lines. Cell permeable.
References/Citations:
γ1) Kodera et al. (2000) Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators; J. Biol. Chem., 275 33201
2) Tchoukalova et al. (2000) Enhancing effect of troglitazone on porcine adipocyte differentiation in primary culture: a comparison with dexamethasone; Obes. Res., 8 664
3) Tsubouchi et al. (2000) Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis; Biochem. Biophys. Res. Commun.270
4) Wyttenbach & Kuentz (2017), Glass-forming ability of compounds in marketed amorphous drug products; Eur. J. Pharm. and Biopharm., 112 204 [Focus Citation]
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