Troleandomycin | Macrolide antibiotic, Inhibits cytochrome P450

CAS:
2751-09-9
Catalog Number:
10-2227
Activity:
Macrolide antibiotic, Inhibits cytochrome P450
Molecular Weight:
813.99
Molecular Formula:
C41H67NO15
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$70.00
25 mg$275.00

Troleandomycin (2751-09-9) is a macrolide antibiotic. Inhibits cytochrome P450 (IC50 = 0-5 μM), thus blocking CYP450-dependent drug oxidation.

References/Citations
1) Patki et al. (2004), Mechanism-based inhibition of CYP3A4 and CYP3A5 by seven inhibitors; Clin. Pharmacol. Therap., 75 P83
2) Kozlov et al. (2003), Various intracellular compartments cooperate in the release of nitric oxide from glycerol trinitrate in liver; Br. J. Pharmacol., 139 989
3) Ludden et al. (1985), Pharmacokinetic interactions of the macrolide antibiotics; Clin. Pharmacokinet., 10 63

CAS:
2751-09-9
Catalog Number:
10-2227
Activity:
Macrolide antibiotic, Inhibits cytochrome P450
Molecular Weight:
813.99
Molecular Formula:
C41H67NO15
Solubility:
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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