TUDCA | ER stress inhibitor
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 500 mg | $45.00 | ||
| 1 gram | $85.00 |
TUDCA (14605-22-2) is a classic inhibitor of endoplasmic reticulum (ER) stress.1 Reduces ER stress and adipose tissue inflammation in a mouse model of high fat diet-induced obesity.2 Blocks ER stress-induced NLRP3 inflammasome activation and hepatocyte death.3 Attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mouse model.4
References/Citations:
1) Xie et al. (2002), Effects of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation; Hepatology, 36 592
2) Chen et al. (2016), Chemical chaperones reduce ER stress and adipose tissue inflammation in high fat diet-induced mouse model of obesity; Sci. Rep., 6 27486
3) Lebeaupin et al. (2015), ER stress induces NLRP3 inflammasome activation and hepatocyte death; Cell Death Dis., 6 e1879
4) Nunes et al. (2012), TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice; Mol. Neurobiol. 45 440
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
TUDCA (14605-22-2) is a classic inhibitor of endoplasmic reticulum (ER) stress.1 Reduces ER stress and adipose tissue inflammation in a mouse model of high fat diet-induced obesity.2 Blocks ER stress-induced NLRP3 inflammasome activation and hepatocyte death.3 Attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mouse model.4
References/Citations:
1) Xie et al. (2002), Effects of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation; Hepatology, 36 592
2) Chen et al. (2016), Chemical chaperones reduce ER stress and adipose tissue inflammation in high fat diet-induced mouse model of obesity; Sci. Rep., 6 27486
3) Lebeaupin et al. (2015), ER stress induces NLRP3 inflammasome activation and hepatocyte death; Cell Death Dis., 6 e1879
4) Nunes et al. (2012), TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice; Mol. Neurobiol. 45 440
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