Size : | Price | Quantity | |
---|---|---|---|
500 mg | $45.00 | ||
1 gram | $85.00 |
TUDCA (14605-22-2) is a classic inhibitor of endoplasmic reticulum (ER) stress.1 Reduces ER stress and adipose tissue inflammation in a mouse model of high fat diet-induced obesity.2 Blocks ER stress-induced NLRP3 inflammasome activation and hepatocyte death.3 Attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mouse model.4
References/Citations:
1) Xie et al. (2002), Effects of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation; Hepatology, 36 592
2) Chen et al. (2016), Chemical chaperones reduce ER stress and adipose tissue inflammation in high fat diet-induced mouse model of obesity; Sci. Rep., 6 27486
3) Lebeaupin et al. (2015), ER stress induces NLRP3 inflammasome activation and hepatocyte death; Cell Death Dis., 6 e1879
4) Nunes et al. (2012), TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice; Mol. Neurobiol. 45 440
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TUDCA (14605-22-2) is a classic inhibitor of endoplasmic reticulum (ER) stress.1 Reduces ER stress and adipose tissue inflammation in a mouse model of high fat diet-induced obesity.2 Blocks ER stress-induced NLRP3 inflammasome activation and hepatocyte death.3 Attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mouse model.4
References/Citations:
1) Xie et al. (2002), Effects of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation; Hepatology, 36 592
2) Chen et al. (2016), Chemical chaperones reduce ER stress and adipose tissue inflammation in high fat diet-induced mouse model of obesity; Sci. Rep., 6 27486
3) Lebeaupin et al. (2015), ER stress induces NLRP3 inflammasome activation and hepatocyte death; Cell Death Dis., 6 e1879
4) Nunes et al. (2012), TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice; Mol. Neurobiol. 45 440
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