Ursolic Acid | Angiogenesis inhibitor

CAS:
77-52-1
Catalog Number:
10-4010
Activity:
Angiogenesis inhibitor
Chemical Name:
3β-Hydroxyurs-12-en-28-oic acid
Molecular Weight:
456.70
Molecular Formula:
C30H48O3
Solubility:
Soluble in DMSO (up to 25 mg/ml with warming)
Physical Properties:
White solid
Purity:
>95% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
50 mg$40.00
250 mg$150.00

Ursolic acid (77-52-1) inhibits endothelial cell proliferation and migration (IC50=5 µM) and angiogenesis.1 Promotes skeletal muscle rejuvenation via enhanced SIRT1 expression.2 Induces apoptosis in malignant mesothelioma cells.3

References/Citations:

1) Sohn et al. (1995), Anti-angiogenic activity of triterpene acids; Cancer Lett., 94 213
2) Bakhtiari et al. (2016), Short-term ursolic acid promotes skeletal muscle rejuvenation through enhancing of SIRT1 expression and satellite cells proliferation; Biomed. Pharmacother., 78 185
3) Sohn et al. (2016), Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell; J. Biol. Sci., 12 1279

CAS:
77-52-1
Catalog Number:
10-4010
Activity:
Angiogenesis inhibitor
Chemical Name:
3β-Hydroxyurs-12-en-28-oic acid
Molecular Weight:
456.70
Molecular Formula:
C30H48O3
Solubility:
Soluble in DMSO (up to 25 mg/ml with warming)
Physical Properties:
White solid
Purity:
>95% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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