Valinomycin | Induces loss of mitochondrial membrane potential
NMR (Conforms)
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| Size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $42.00 | ||
| 50 mg | $140.00 |
Valinomycin (2001-95-8) is a selective K+ ionophore capable of transporting potassium ions through lipid membranes.1 Valinomycin can induce apoptosis in cells by causing a rapid loss of mitochondrial membrane potential via potassium efflux.2,3
References/Citations:
1) Pressman, (1976) Biological applications of ionophores; Annu. Rev. Biochem., 45 501
2) Furlong et al., (1998) Induction of apoptosis by valinomycin: mitochondrial permeability transition causes intracellular acidification; Cell Death Diff., 5 214
3) Inai et al. (1997) Valinomycin induces apoptosis of ascites hepatoma cells (AH-130) in relation to mitochondrial membrane potential; Cell Struc. Funct., 22 555
NMR (Conforms)
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Valinomycin (2001-95-8) is a selective K+ ionophore capable of transporting potassium ions through lipid membranes.1 Valinomycin can induce apoptosis in cells by causing a rapid loss of mitochondrial membrane potential via potassium efflux.2,3
References/Citations:
1) Pressman, (1976) Biological applications of ionophores; Annu. Rev. Biochem., 45 501
2) Furlong et al., (1998) Induction of apoptosis by valinomycin: mitochondrial permeability transition causes intracellular acidification; Cell Death Diff., 5 214
3) Inai et al. (1997) Valinomycin induces apoptosis of ascites hepatoma cells (AH-130) in relation to mitochondrial membrane potential; Cell Struc. Funct., 22 555
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