WIN-55212-2 mesylate | Cannabinoid CB1/CB2 agonist
NMR (Conforms)
Available Options
| size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $70.00 | ||
| 50 mg | $280.00 |
WIN-55212-2 mesylate (131543-23-2) is a high affinity cannabinoid receptor agonist (Ki = 62.3 nM for recombinant human CB1 and 3.3 nM for recombinant human CB2)1 with analgesic2 and anti-inflammatory activities. WIN-55212-2 mesylate activates p42 and p44 MAP kinase via cannabinoid receptor-mediated receptor signaling.3
References/Citations:
1) Felder et al. (1995), Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2receptors; Mol. Pharmacol., 48 443
2) Herzberg et al. (1997), The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist in a rat model of neuropathic pain; Neurosci. Lett., 221 157
3) Bouaboula et al. (1995), Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1; Biochem. J., 312 637
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
WIN-55212-2 mesylate (131543-23-2) is a high affinity cannabinoid receptor agonist (Ki = 62.3 nM for recombinant human CB1 and 3.3 nM for recombinant human CB2)1 with analgesic2 and anti-inflammatory activities. WIN-55212-2 mesylate activates p42 and p44 MAP kinase via cannabinoid receptor-mediated receptor signaling.3
References/Citations:
1) Felder et al. (1995), Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2receptors; Mol. Pharmacol., 48 443
2) Herzberg et al. (1997), The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist in a rat model of neuropathic pain; Neurosci. Lett., 221 157
3) Bouaboula et al. (1995), Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1; Biochem. J., 312 637
Related products
-
LY171883 | Cys LT1 antagonist
From $60.00CAS:88107-10-2Catalog Number:10-1052Activity:Cys LT1 antagonistChemical Name:1-[2-Hydroxy-3-propyl-4-[4-1H-tetrazol-5-yl)butoxy]phenyl]ethanoneMolecular Weight:318.37Molecular Formula:C16H22N4O3Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml),Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°C (des.)Stability:Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 monthsShipping Code:RT -
Reversine | Reverses differentiated cells to multipotent stem cells
From $75.00CAS:656820-32-5Catalog Number:10-1154Activity:Reverses differentiated cells to multipotent stem cellsChemical Name:2-(4-Morpholinoanilino)-6-cyclohexylaminopurineMolecular Weight:383.5Molecular Formula:C21H27N7OSolubility:Soluble in DMSO (up to 7 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 monthsShipping Code:RT -
SR-144528 | Cannabinoid CB2 antagonist
From $100.00CAS:192703-06-3Catalog Number:10-1164Activity:Cannabinoid CB2 antagonistChemical Name:5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamideMolecular Weight:476.07Molecular Formula:C29H34ClN3OSolubility:Soluble in DMSO (up to 20 mg/ml, with warming).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
Calculate the molar concentration, mass or volume in a solution.
Concentration × Volume × Molecular Weight = Mass
