XAV-939 | Tankyrase inhibitor/Cardiomyogenesis inducer
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 5 mg | $50.00 | ||
| 25 mg | $150.00 |
XAV-939 (284028-89-3) is a tankyrase inhibitor (IC50=11 and 4 nM for TNKS1 and 2 respectively). Antagonizes wnt signaling via stimulation of β-catenin degradation and stabilization of actin.1 XAV-939 robustly induces cardiomyogenesis of stem cells.2 Cell permeable
References/Citations:
1) Huang et al. (2009), Tankyrase inhibition stabilizes axin and antagonizes Wnt signaling; Nature, 46 614
2) Wang et al. (2011), Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/β-catenin signaling; Chem. Biol., 6 192
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
XAV-939 (284028-89-3) is a tankyrase inhibitor (IC50=11 and 4 nM for TNKS1 and 2 respectively). Antagonizes wnt signaling via stimulation of β-catenin degradation and stabilization of actin.1 XAV-939 robustly induces cardiomyogenesis of stem cells.2 Cell permeable
References/Citations:
1) Huang et al. (2009), Tankyrase inhibition stabilizes axin and antagonizes Wnt signaling; Nature, 46 614
2) Wang et al. (2011), Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/β-catenin signaling; Chem. Biol., 6 192
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1-855-FOCUS21
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