Zebularine | DNA methylation inhibitor

CAS:
3690-10-6
Catalog Number:
10-2432
Activity:
DNA methylation inhibitor
Alternate Names:
NSC 309132
Chemical Name:
1H-β-D-Ribofuranosyl-2-pyrimidinone
Molecular Weight:
228.21
Molecular Formula:
C9H12N2O5
Solubility:
Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
5 mg$60.00
25 mg$240.00

Zebularine (3690-10-6) is an orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates silenced genes in T24 bladder carcinoma cells. Zebularine inhibits cytidine deaminase (Ki ~ 2 μM and; induces differentiation of mesenchymal stem cells into cardiomyocytes.

CAS:
3690-10-6
Catalog Number:
10-2432
Activity:
DNA methylation inhibitor
Alternate Names:
NSC 309132
Chemical Name:
1H-β-D-Ribofuranosyl-2-pyrimidinone
Molecular Weight:
228.21
Molecular Formula:
C9H12N2O5
Solubility:
Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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