Zerumbone | Enhances apoptosis

CAS:
471-05-6
Catalog Number:
10-2247
Activity:
Enhances apoptosis
Chemical Name:
(2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
Molecular Weight:
218.34
Molecular Formula:
C15H22O
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
95% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
10 mg$50.00
50 mg$190.00

Zerumbone (471-05-6) is a natural sesquiterpene ketone isolated from Zingiber sp. Potentiates TRAIL-induced apoptosis via upregulation of death receptor DR4 and DR5 expression. Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells but has no cytotoxic effect on normal cells. Cell permeable.

References/Citations:

1) Leu et al. (2009), A small molecule inhibitor of inducible heat shock protein 70; Mol. Cell, 36 15
2) Abdelwahab et al. (2011), Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells; Leuk. Res., 35 268

CAS:
471-05-6
Catalog Number:
10-2247
Activity:
Enhances apoptosis
Chemical Name:
(2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
Molecular Weight:
218.34
Molecular Formula:
C15H22O
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
95% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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