Zolmitriptan | Serotonin 5HT1B/1D receptor agonist / Regenerative activity
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 10 mg | $50.00 | ||
| 50 mg | $200.00 |
Zolmitriptan (CAS 139264-17-8) is a potent and selective serotonin 5HT 1B/1D agonist (Ki=0.63 and 5.01 nM for 5HT 1D and 1B respectively.1 Displays proven efficacy for the treatment of migraine.2 Inhibits neurogenic inflammation and pain during electrical stimulation in human skin.3 Induces nerve growth, integration and function in transplanted heterologous organs in regenerative medicine.4
References/Citations:
1) Pauwels et al. (1997), How efficacious are 5-HTB/D receptor ligands: an answer from GTP gamma S binding studies with stably transfected C6-glial cell lines; Pharmacol., 36 499
2) Martin et al. (1997), Receptor specificity and trigemino-vascular inhibitor actions of a novel 5HT1B/1D receptor partial agonist, 311C90 (zolmitriptan); Br. J. Pharmacol., 121 157
3) Doring et al. (2015), Zolmitriptan inhibits neurogenic inflammation and pain during electrical stimulation in human skin; Eur. J. Pain, 19 966
4) Blackiston et al. (2017), Serotonergic stimulation induces nerve growth and promotes visual learning via posterior eye grafts in a vertebrate model of induced sensory plasticity; Regenerative Med., 2 8
NMR (Conforms)
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Product Data Sheet:
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Zolmitriptan (CAS 139264-17-8) is a potent and selective serotonin 5HT 1B/1D agonist (Ki=0.63 and 5.01 nM for 5HT 1D and 1B respectively.1 Displays proven efficacy for the treatment of migraine.2 Inhibits neurogenic inflammation and pain during electrical stimulation in human skin.3 Induces nerve growth, integration and function in transplanted heterologous organs in regenerative medicine.4
References/Citations:
1) Pauwels et al. (1997), How efficacious are 5-HTB/D receptor ligands: an answer from GTP gamma S binding studies with stably transfected C6-glial cell lines; Pharmacol., 36 499
2) Martin et al. (1997), Receptor specificity and trigemino-vascular inhibitor actions of a novel 5HT1B/1D receptor partial agonist, 311C90 (zolmitriptan); Br. J. Pharmacol., 121 157
3) Doring et al. (2015), Zolmitriptan inhibits neurogenic inflammation and pain during electrical stimulation in human skin; Eur. J. Pain, 19 966
4) Blackiston et al. (2017), Serotonergic stimulation induces nerve growth and promotes visual learning via posterior eye grafts in a vertebrate model of induced sensory plasticity; Regenerative Med., 2 8
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